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Taking these drugs together may significantly decrease ledipasvir plasma concentrations, potentially resulting in loss of antiviral efficacy. (Major) Avoid coadministration of sofosbuvir, a P-glycoprotein (P-gp) substrate, with inducers of P-gp, such as rifampin.
Aubagio is used to reduce flare-ups in people with relapsing MS. Aubagio is not a cure for MS. Descovy is a two-drug combination of Emtricitabine (FTC) and Tenofovir Alafenamide (TAF). It can also replace the current antiretroviral regimen in those who are virologically-s Harvoni is a fixed-dose combination of Ledipasvir, a hepatitis C virus (HCV) NS5A inhibitor, and Sofosbuvir, an HCV nucleotide analog NS5B polymerase It may be used as monotherapy or in combination with methotrexate or.
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